金银花与山银花化学成分及其差异的研究进展

发布时间：2018-02-13 13:37:20 来源：文档文库

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金银花与山银花化学成分及其差异的研究进展

作者：杨倩茹　赵媛媛　郝江波　李卫东

来源：《中国中药杂志》2016年第07期

[摘要]金银花与山银花是忍冬科忍冬属不同种植物来源的干燥花蕾或带初开的花，二者为2味药材，而其功效均为“清热解毒，疏散风热”，由于种种原因，二者争议很大。该文综述了金银花与山银花的药效物质基础——化学成分及其差异的研究进展，在有机酸类、黄酮类、三萜皂苷类、环烯醚萜类、挥发油类及微量元素等化学成分组成及含量上，二者有相同或相似之处，但也存在一定差异。二者主要差异：金银花较山银花含有较丰富的环烯醚萜类和黄酮类化合物，而山银花中三萜皂苷类化合物种类较多；山银花中绿原酸含量明显高于金银花；金银花中芦丁、木犀草苷、木犀草素7OβD半乳糖苷、忍冬苷含量远高于山银花；金银花中铁（Fe）与镍（Ni）含量较山银花中高，而山银花中锰（Mn）含量较金银花中高。该文最后提出在化学成分研究方面，金银花与山银花存在的主要问题及建议。

[关键词]金银花；山银花；化学成分；差异

[Abstract]The dried flower buds or initial flowers of Lonicerae Japonicae Flos and Lonicerae Flos， which belong to different species of Lonicera or Caprifoliaceae，are usually taken to clear away heat and toxic material and treat the exopathogenic windheat They are two different herbs， and due to various reasons， there are far more controversies This paper reviews the research on the chemical constituents and their differences between Lonicerae Japonicae Flos and Lonicerae Flos Both of them contain the similar chemical constituents， such as organic acids， flavonoids， triterpenoidal saponins， iridoids， volatile oils and trace elements But there are also differences between them The main differences：Lonicerae Japonicae Flos contains a wealth of iridoids and flavonoids， while Lonicerae Flos contains more kinds of triterpenoidal saponins； the content of chlorogenic acid in Lonicerae Flos is significantly higher than that of Lonicerae Japonicae Flos； the content of rutin， luteoloside，luteolin7OβDgalactoside and lonicerin in Lonicerae Japonicae Flos is much higher than that of Lonicerae Flos； the content of Fe and Ni in Lonicerae Japonicae Flos is higher， while the content of Mn is higher in Lonicerae Flos Finally， main problems and suggestions on chemical composition between Lonicerae Japonicae Flos and Lonicerae Flos were also discussed