Product Name:Fluticasone propionate CAS No.:80474-14-2Cat. No.:HY-B0154Product Data SheetMWt:500.57Formula:C25H31F3O5S Purity :>98%Solubility:DMSO 100 mg/mL (199 mM);Mechanisms:Biological Activity:Fluticasone propionate is a high affinity selective GR (glucocorticoid receptor)agonist which isPathways:GPCR/G protein; Target:Glucocorticoid Receptor Water <1 mg/mL (<1 mM)Fluticasone propionate is a high affinity, selective GR (glucocorticoid receptor) agonist which isderived from fluticasone used to treat asthma and allergic rhinitis.Target: Glucocorticoid Receptor Fluticasone propionate is a corticosteroid derived from fluticasone used to treat asthma and allergic rhinitis. It is also used to treat eosinophilic esophagitis. Fluticasone propionate is a synthetictrifluorinated glucocorticoid. It is highly lipophilic (logp octanol/water 3.69). In studies the topical drug has been associated with burning, stinging, skin irritation, blisters, dryness, skin infection, infected eczema, viral warts,impetigo, atopic dermatitis, pruritus, exacerbation of pruritus, exacerbation ofeczema, erythema, and folliculitis.References:[1]. McKeage K. Fluticasone propionate/formoterol fumarate: a review of its use in persistentasthma. Drugs. 2013 Feb;73(2):195-206.There are also numerous side effects associated with the oral version of this medication including headache, stuffy or runny no...Caution: Not fully tested. For research purposes onlyMedchemexpress LLCwww.medchemexpress.com18W i l k i n s o n W a y , P r i n c e t o n , N J 08540,U S AE m a i l : i n f o @m e d c h e m e x p r e s s .c o m W e b : w w w .m e d c h e m e x p r e s s .c o m
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