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Beta-ALANINE DERIVATIVE AND USE THEREOF

发布时间：2023-01-19 16:49:48 来源：文档文库

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Beta-ALANINEDERIVATIVEANDUSETHEREOF
申请(专利号：
AU20030241833专利号：AU2003241833A1主分类号：
C07C233/83申请日：2003-05-28公开公告日：
2003-12-12分类号：
C07C233/83;A61P27/06;A61P29/00;A61P35/00;A61P35/02;A61P35/04;A61P37/00;A61P43/00;C07C311/46;C07D209/16;C07D213/40;C07D217/06;C07D307/52;C07D333/20;C07D401/12;C07D405/12;C07D409/12;C07D471/04;A61K31/197;A61K31/22;A61K31/222;A61K31/341;A61K31/381;A61K31/4045;A61K31/437;A61K31/4402;A61K31/4406;A61K31/4409;A61K31/443;A61K31/4436;A61K31/4439;A61K31/444;A61K31/472;A61K31/4725;A61P1/16;A61P3/10;A61P5/14;A61P9/02;
申请权利人：
ONOPHARMACEUTICALCO.,LTD.公开国代码：AU优先权国家：
JP摘要：
Acompoundofthegeneralformula(I(whereinthesymbolsareasdefinedinthedescription,oraprodrugorasaltthereof.ThiscompoundengagesinLPAreceptorbondingandantagonismandhenceisusefulinthepreventionand/ortreatmentofurinarysystemdisease(symptomwithprostatichypertrophyorneurogenicbladderdysfunctiondisease,symptomtobecausedbyspinalcordneoplasm,nucleoushernia,spinalcanalstenosisordiabetes,lowerurinarytractsymptom(forA61P9/10;A61P9/14;A61P11/00;A61P13/00;A61P13/02;A61P13/08;A61P13/10;A61P13/12;A61P17/06;A61P19/10;A61P25/00;A61P25/02;A61P25/16;A61P25/28;A61P27/02发明设计人：
HIROMUHABASHITA;MASAHIKOTERAKADO;SHINJINAKADE;TAKUYASEKO申请国代码：
AU优先权：
20020528JP2002153592;20030528JP0306678摘要附图：

example,occlusiondiseaseoflowerurinarytract,inflammatorydiseaseoflowerurinarytract,polyuria,carcinomaassociationdisease(solidtumor,solidtumormetastasis,angiofibroma,myeloma,multiplemyeloma,Kaposi'ssarcoma,leucemiaandcarcinomatousinfiltrationtransition,proliferativedisease(disorderwithaberrantangiogenesis,arteryobstructionandpulmonaryfibrosis,inflammation/immunesystemdisease(psoriasis,nephropathy,hepatitisandpneumonitissymptom,diseasebysecretionfault(Sjogrensyndromeorbrainassociationdisease(braininfarction,cerebralapoplexyandbrainorperipheralneuropathy.主权项：

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